Oct 8, 2020 1:1 Na+:Glu. Glucose transporters (GLUT). function. facilitated diffusion of glucose down concentration gradients. with increasing glucose
ANTI-GLUCOSE TRANSPORTER-1 RABBIT PAB. REACH- registreringsnummer: Det finns inget registreringsnummer för denna substans
14 May 2020 GLUT1 (glucose transporter isoform 1/Slc2a1) is highly expressed in ECs of the central nervous system (CNS) and is often implicated in GLUCOSE TRANSPORTER 1; GLUT; GLUT1 ERYTHROCYTE/HEPATOMA GLUCOSE TRANSPORTER HUMAN T-CELL LEUKEMIA VIRUS RECEPTOR; HTLVR Genetic testing for the SLC2A1 gene, whose pathogenic variants cause glucose transporter type 1 deficiency syndrome (GLUT1DS). 6 Sep 2005 Glucose transporter 1 expression identifies a population of cycling CD4+CD8+ human thymocytes with high CXCR4-induced chemotaxis. 23 Mar 2020 GLUT-1 was an independent prognosis factor in locally advanced gastric cancer patients who had undergone radical gastrectomy (hazard ratio [ Rabbit polyclonal Glucose Transporter GLUT1 antibody. Validated in ICC/IF and tested in Human. Cited in 183 publication(s).
Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes (англ.) Se hela listan på epilepsy.org.uk Sodium-dependent glucose transporter 2 (SGLT2) plays an important role in the regulation of blood glucose.1 It is expressed predominantly in the kidney where it reabsorbs approximately 90% of the filtered glucose load. In patients with type 2 diabetes, SGLT2 is overexpressed and glucose re-absorption continues, exacerbating hyperglycaemia.2 Glucose transporter type 4 (GLUT-4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin -regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). 2015-02-17 · Keywords LX4211, sotagliflozin, sodium-glucose transporter 1, sodium-glucose transporter 2, diabetes mellitus, type 1, diabetes mellitus type 2, glucagon-like peptide 1 Introduction Sodium-dependent glucose transporter 2 (SGLT2) plays an important role in the regulation of blood glucose. 1 It is expressed predominantly in the kidney where it reabsorbs approximately 90% of the filtered glucose Several studies have found that increased glucose transporter‑1 (GLUT‑1) expression is associated with radioresistance.
Se hela listan på epilepsy.org.uk Sodium-dependent glucose transporter 2 (SGLT2) plays an important role in the regulation of blood glucose.1 It is expressed predominantly in the kidney where it reabsorbs approximately 90% of the filtered glucose load.
Glucose Transporter-1 (GLUT-1) by Immunohistochemistry Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a
Hypoxia-inducible factor-1 (HIF-1), glucose transporter-1 (GLUT-1), and carbon anhydrase IX (CAIX) are important molecules that allow adaptation to hypoxic environments.The aim of our study was to investigate the correlation between HIF-1, GLUT-1, and CAIX protein level with the clinicopathological features of endometrial cancer patients. 2011-07-25 2010-04-13 We show that facilitative glucose transporter 1 (Glut1) localizes to mitochondria in mammalian cells and participates in the mitochondrial transport of vitamin C. Our theoretical analysis and experimental studies of chimeric Glut1‐EGFP localization indicate a role of N‐terminal Glut1 in mitochondrial targeting.
Glucose transporter 1 (GLUT1) is a facilitative glucose transporter To find out the most favorable GLUT 1 conformation for ligand binding, we ran systemic
GLUT-1 Protein. GLUT1 Protein. SLC2A1 Protein.
Visar resultat 1 - 5 av 33 avhandlingar innehållade orden glucose transporter 4. 1. Quantitation, Purification and Reconstitution
Q0WUU6 · Arabidopsis thaliana, 1, 100%, Probable polyol transporter 4 thaliana, 0.068, Probable plastidic glucose transporter 1, PLST1_ARATH (UniProt). Because of the effective catabolism ofd-glucose to short-chain fatty acids by intraruminal microorganisms, In conclusion, the ruminal epithelium has a high-affinity SGLT-1, which indicates that it maintains the Sodium-Glucose Transporter 1. In the placenta of PS rats, the expression of glucose transporter type 1 (GLUT1) was decreased, whereas GLUT3 and GLUT4 were slightly increased. Moreover
av O Idås — Diabetes typ 1 orsakas av defekta β-celler i bukspottkörteln som fettceller normalt leder till transport av GLUT4 (Glucose transporter type 4) till cellmembranet. Över-föringen av glukos från moderns cirkulation sker genom faciliterad diffusion med hjälp av fram-förallt av glukostransportören GLUT 1 (2).
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The amino acid sequence of GLUT1 is highly conserved and 98% identity exists between the sequences of human and rat GLUT1 and 97% identity between the sequences of human and mouse, rabbit, or pig. Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene. GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells.
Glucose transporter 1 (GLUT1), a ubiquitously expressed glucose transporter, is strongly upregulated after innate and adaptive immune cell activation. Deletion or inhibition of GLUT1 blocked T cell proliferation and effector function, antibody production from B cells and reduced inflammatory responses in macrophages. This gene provides instructions for producing a protein called the glucose transporter protein type 1 (GLUT1). The GLUT1 protein is embedded in the outer membrane surrounding cells , where it transports a simple sugar called glucose into cells from the blood or from other cells for use as fuel.
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A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo Yi Liu 1,5, Yanyan Cao , Weihe Zhang2, Stephen Bergmeier2, Yanrong Qian2,5, Huzoor Akbar3, Robert Colvin 1,5, Juan Ding , Lingying Tong 2,5, Shiyong Wu2,5, Jennifer Hines , and Xiaozhuo
Created using PowToon.CO An overview of the two families of glucose transporters, their modes of transportation, and their function in the body. There are two mechanisms for glucose transport across cell membranes. In the intestine and renal proximal tubule, glucose is transported against a concentration gradient by a secondary active transport mechanism in which glucose is cotransported with sodium ions. In all other cells, glucose transport is mediated by one or more of the members of the closely related GLUT family of glucose Glucose transporter type 1 deficiency syndrome (GLUT1-DS) is a treatable metabolic disorder caused by mutation in the SLC2A1 gene. The functional deficiency of the GLUT1 protein leads to impaired glucose transport into the brain, resulting in a spectrum of neurological phenotypes. Glukose er hjernens viktigste energikilde.